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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT5B
All Species:
32.12
Human Site:
Y249
Identified Species:
58.89
UniProt:
Q9H1J7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1J7
NP_110402.2
359
40323
Y249
G
D
R
L
K
E
K
Y
D
S
A
A
A
M
R
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
N239
D
Y
L
W
R
K
Y
N
G
A
I
Q
V
V
M
Rhesus Macaque
Macaca mulatta
XP_001117880
429
46995
Y319
G
D
R
L
K
E
K
Y
D
S
A
A
A
M
R
Dog
Lupus familis
XP_541837
360
40483
Y250
G
D
A
L
K
E
K
Y
D
S
A
A
A
M
R
Cat
Felis silvestris
Mouse
Mus musculus
P22726
359
40325
Y249
G
D
R
L
K
E
K
Y
D
S
A
A
A
M
R
Rat
Rattus norvegicus
Q9QXQ7
380
42265
Y270
G
D
A
L
K
E
K
Y
D
S
A
A
A
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
N240
D
Y
L
W
R
K
Y
N
G
A
I
Q
V
V
M
Chicken
Gallus gallus
P49337
351
38945
A241
L
K
E
K
F
D
G
A
T
E
V
E
Q
S
E
Frog
Xenopus laevis
P33945
360
40662
Y250
G
E
Y
I
K
E
K
Y
D
S
A
A
S
M
R
Zebra Danio
Brachydanio rerio
Q92050
363
41119
Y253
G
E
F
L
K
E
K
Y
D
S
A
A
A
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397473
422
46971
Y312
G
D
F
L
L
D
K
Y
D
G
A
T
E
V
R
Nematode Worm
Caenorhab. elegans
P34889
360
40418
R250
N
K
Y
D
K
A
I
R
V
Q
I
N
D
R
G
Sea Urchin
Strong. purpuratus
XP_779946
415
46408
Y305
G
T
I
L
K
D
K
Y
D
G
A
T
N
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.5
74.1
80.2
N.A.
94.1
76.8
N.A.
48.7
48.1
83.6
79.6
N.A.
N.A.
52.1
45.5
55.6
Protein Similarity:
100
63.3
78.3
89.1
N.A.
97.7
85
N.A.
63.7
62.9
91.1
89.2
N.A.
N.A.
65.6
66.9
68.6
P-Site Identity:
100
0
100
93.3
N.A.
100
93.3
N.A.
0
0
73.3
86.6
N.A.
N.A.
53.3
6.6
53.3
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
93.3
N.A.
26.6
6.6
93.3
93.3
N.A.
N.A.
66.6
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
0
8
0
16
70
54
47
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
47
0
8
0
24
0
0
70
0
0
0
8
0
0
% D
% Glu:
0
16
8
0
0
54
0
0
0
8
0
8
8
0
8
% E
% Phe:
0
0
16
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
70
0
0
0
0
0
8
0
16
16
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
8
0
0
0
24
0
0
0
0
% I
% Lys:
0
16
0
8
70
16
70
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
16
62
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
16
% M
% Asn:
8
0
0
0
0
0
0
16
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
16
8
0
0
% Q
% Arg:
0
0
24
0
16
0
0
8
0
0
0
0
0
8
70
% R
% Ser:
0
0
0
0
0
0
0
0
0
54
0
0
8
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
8
0
0
16
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
8
0
16
31
0
% V
% Trp:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
16
0
0
0
16
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _